A re-examination of proliferation and differentiation of type A spermatogonia in the adult rhesus monkey (Macaca mulatta)

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A re-examination of proliferation and differentiation of type A spermatogonia in the adult rhesus monkey (Macaca mulatta).

BACKGROUND Companion studies using an experimental non-human primate paradigm known as a testicular clamp indicated that the behavior of undifferentiated type A spermatogonia did not conform fully to earlier classical models. This issue was therefore re-examined in normal monkeys. METHODS Adult male rhesus monkeys (n = 4) received an i.v. bolus of 5-bromo-2'-deoxyuridine (BrdU): one testis (f...

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A selective monotropic elevation of FSH, but not that of LH, amplifies the proliferation and differentiation of spermatogonia in the adult rhesus monkey (Macaca mulatta).

BACKGROUND Unilateral orchidectomy in monkeys increases spermatogenesis in the remaining testis in association with elevated follicle-stimulating hormone (FSH) secretion and testicular testosterone. The present study examined the relative importance of FSH and testosterone in driving the primate testis toward its spermatogenic ceiling. METHODS Adult male rhesus monkeys were treated with a gon...

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The testicular transcriptome associated with spermatogonia differentiation initiated by gonadotrophin stimulation in the juvenile rhesus monkey (Macaca mulatta).

STUDY QUESTION What is the genetic landscape within the testis of the juvenile rhesus monkey (Macaca mulatta) that underlies the decision of undifferentiated spermatogonia to commit to a pathway of differentiation when puberty is induced prematurely by exogenous LH and FSH stimulation? SUMMARY ANSWER Forty-eight hours of gonadotrophin stimulation of the juvenile monkey testis resulted in the ...

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Canine Distemper in the Rhesus Monkey (macaca Mulatta)

Canine distemper has been transmitted to rhesus monkeys by a variety of methods. The disease is strikingly similar if not identical in its features with distemper in dogs.

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2009

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/dep051